Written by Dr Vahe

Introduction
Polynucleotides have revolutionised aesthetic medicine, offering natural, regenerative solutions for skin and hair rejuvenation. These biocompatible treatments, derived from DNA or RNA fragments, work by hydrating, repairing, and supporting tissue regeneration. By stimulating collagen production and improving skin elasticity, polynucleotides are an excellent alternative to traditional fillers and are suitable for various areas and concerns.

At Astrum Medical, we are proud to offer the most advanced polynucleotide treatments, ensuring our clients achieve tailored, effective results with the highest-quality brands.

What Are Polynucleotides?

Polynucleotides are fragments of DNA or RNA that promote skin repair, hydration, and regeneration. By activating fibroblasts and supporting cellular regeneration, they help reduce fine lines, improve elasticity, and even stimulate hair growth.

Top Polynucleotide Brands and Their Types

Here’s a breakdown of the most popular brands, their specific types, and the concerns they address.

1. Rejuran

Origin: South Korea
Overview: Rejuran features high-purity salmon DNA for regenerative and anti-inflammatory effects.

Types:

• Rejuran Healer: For overall facial rejuvenation, targeting fine lines, large pores, and scars.
• Rejuran I: Specially designed for the delicate under-eye area, improving hydration and minimising fine lines.
• Rejuran S: Effective for acne scars and deep scar healing.

Best for: Rejuran Healer for facial repair, Rejuran I for under-eyes, and Rejuran S for scar treatment.

2. Plenhyage

Origin: Italy
Overview: Plenhyage is focused on collagen stimulation and improving skin elasticity, making it suitable for anti-ageing treatments.

Types:

• Plenhyage Medium: Ideal for mild signs of ageing on the face and neck.
• Plenhyage Strong: Offers intense lifting and firmness, targeting mature skin on the neck, décolletage, and hands.

Best for: Plenhyage Medium for early anti-ageing signs and Plenhyage Strong for mature skin rejuvenation.

3. Nucleofill

Origin: Italy
Overview: Nucleofill combines hydration, lifting, and protection, with formulations for both skin and hair rejuvenation.

Types:

• Nucleofill Light: Ideal for sensitive areas like the eyes and lips.
• Nucleofill Hair: Designed to revitalise the scalp and stimulate stronger hair growth.
• Nucleofill Strong (25 mg): Offers deep lifting and hydration for mature or dehydrated skin.

Best for: Nucleofill Light for delicate anti-ageing, Nucleofill Hair for scalp health, and Nucleofill Strong for advanced facial rejuvenation.

4. Chroma PhilArt

Origin: Austria (by Croma-Pharma)
Overview: Chroma PhilArt combines polynucleotides with antioxidants for skin rejuvenation and protection.

Types:

• PhilArt: For general skin rejuvenation, improving hydration and elasticity.
• PhilArt Eye: Specially designed for the delicate under-eye area, reducing puffiness and dark circles.
• PhilArt Skin Booster: Enhances overall skin quality, delivering hydration and firmness.

Best for: PhilArt for overall rejuvenation, PhilArt Eye for under-eye treatment, and PhilArt Skin Booster for skin improvement.

5. Plinest

Origin: Italy (by Mastelli)
Overview: Plinest, made from salmon DNA, offers diverse formulations for hydration, lifting, and targeted treatments for skin and hair concerns.

Types:

• Plinest Classic: Improves skin radiance, elasticity, and targets signs of ageing like fine lines and uneven texture.
• Plinest Fast: A concentrated formula for quicker results, ideal for the face and neck, especially for eye bags and dark circles.
• Plinest Eyes: Specifically for the delicate under-eye area, refreshing and smoothing the skin.
• Plinest Body: Designed for larger areas, such as arms and knees, where the skin is thicker than the face.
• Plinest Newest: Combines hyaluronic acid and mannitol, targeting older patients with dry skin.
• Plinest Hair: Stimulates hair follicle growth and helps manage hair loss.
• Plinest One: Reduces the appearance of stretch marks by promoting collagen and elastin production.

Best for: Plinest Classic for general anti-ageing, Plinest Fast for quick results, Plinest Eyes for under-eyes, Plinest Body for thicker skin areas, and Plinest Hair for scalp health.

6. Ameela

Origin: Italy
Overview: Ameela stands out for its versatile formulations designed for comprehensive rejuvenation, hydration, and lifting across different areas of the body.

Types:

• Ameela Face Rejuvenation: Focused on facial anti-ageing and hydration.
• Ameela Eyes: Targets puffiness and dark circles under the eyes.
• Ameela Eyes/Face/Neck/Hair: A multi-use formulation for comprehensive rejuvenation.
• Ameela Body: Treats larger areas like arms and abdomen for improved firmness and tone.

Best for: Ameela offers an all-encompassing solution for face, body, and hair. Its versatility and effectiveness make it the best polynucleotide treatment option for clients seeking comprehensive results.

7. Lumi Eyes

Origin: South Korea
Overview: Lumi Eyes treats under-eye puffiness, dark circles, and fine lines with a focus on hydration and brightening.

Best for: Under-eye rejuvenation and hydration.

8. Ami Eyes

Origin: South Korea
Overview: Combines polynucleotides with brightening agents for enhanced under-eye revitalisation.

Best for: Brightening and hydrating tired under-eyes.

9. Pure Eyes

Origin: South Korea
Overview: Provides deep hydration and repair for the thin, delicate under-eye skin.

Best for: Hydrating and firming the under-eye area.

Why Choose Ameela at Astrum Medical?

At Astrum Medical, we offer the full range of polynucleotide treatments, including the highly versatile and effective Ameela. Whether you’re targeting the face, under-eye area, body, or hair, Ameela’s comprehensive formulations deliver natural, long-lasting results.

Book your consultation today at Astrum Medical and discover how polynucleotides like Ameela can transform your skin and hair.